MODEL AND OBSERVED STATISTICS OF CALIFORNIA EARTHQUAKES PARAMETERS


Targeting Hedgehog Signalling through the Ubiquitylation Process: The Multiple Roles of the HECT-E3 Ligase Itch

Hedgehog signalling (Hh) is a developmental conserved pathway strongly involved in cancers when deregulated.This important pathway is orchestrated by numerous regulators, transduces through distinct routes and is finely tuned at multiple levels.In this regard, ubiquitylation processes stand as essential for controlling Hh pathway output.Although th

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A national evaluation analysis and expert interview study of real-world data sources for research and healthcare decision-making

Abstract Real-world data (RWD) can provide intel (real-world evidence, RWE) for research and development, as well as policy and regulatory decision-making along the full spectrum of health care.Despite calls from global regulators for international collaborations to integrate RWE into regulatory decision-making and to bridge knowledge gaps, some ch

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Effects of food availability on yolk androgen deposition in the black-legged kittiwake (Rissa tridactyla), a seabird with facultative brood reduction.

In birds with facultative brood reduction, survival of the junior chick is thought to be regulated primarily by food availability.In black-legged kittiwakes (Rissa tridactyla) where parents and chicks are provided with unlimited access to supplemental food during the breeding season, brood reduction still occurs and varies interannually.Survival of

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